ALEXIS Biochemicals: 8-Bromoguanosine-3',5'-cyclic Monophosphate . sodium salt

ALX-480-006

Revised 22-Oct-08

8-Bromoguanosine-3',5'-cyclic Monophosphate . sodium salt
SYNONYMS	8-Br-cGMP . Na
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	cGMP Derivatives

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-480-006-M010		10 mg	48.00 USD
ALX-480-006-M050		50 mg	145.00 USD

Product Specification

FORMULA:	C₁₀H₁₀BrN₅O₇P . Na
MW:	423.1 . 23.0
CAS NUMBER:	51116-01-9
PURITY:	≥99% (HPLC)
APPEARANCE:	White to off-white powder.
PURITY DETAIL:	Low in fluorescent and colored impurities.
SOLUBILITY:	Soluble in water or aqueous buffers.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
IDENTITY:	Identity determined by ¹H-NMR, MS and UV.

Product Description

Activator of cGMP-dependent protein kinases (PKGs) 1α, 1β and type II and cGMP-gated ion channels (cGMP agonist). Has increased metabolic stability and membrane permeability compared to cGMP (Prod. No. ALX-480-059).

Product Specific Literature References

Sodium nitroprusside-induced protein phosphorylation in intact rat aorta is mimicked by 8-bromo cyclic GMP: R.M. Rapoport, et al.; PNAS 79, 6470 (1982) Abstract
The nitric oxide--cyclic GMP pathway and synaptic depression in rat hippocampal slices: C.L. Boulton, et al.; Eur. J. Neurosci. 6, 1528 (1994) Abstract
Nitric oxide in skeletal muscle: L. Kobzik, et al.; Nature 372, 546 (1994) Abstract
Nitric oxide. More jobs for that molecule: S. Snyder; Nature 372, 504 (1994) Abstract

Further Categories Containing This Product:

PKG Activators

header picture © micronaut.ch, another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.