ALEXIS Biochemicals: Monoclonal Antibody to NS3 (HCV) (1B6)

ALX-803-059

Revised 27-Apr-06

Monoclonal Antibody to NS3 (HCV) (1B6)
SYNONYMS	anti-Nonstructural Protein 3 (HCV) MAb (1B6)
PRODUCT LINE	Viral Signalling
PRODUCT CATEGORY	Hepatitis Viruses / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-803-059-R100		100 µl	360.00 USD

Product Specification

CLONE:	1B6
ISOTYPE:	Mouse IgG1
PURITY:	Liquid. Ascites fluid diluted in PBS containing 0.02% sodium azide.
IMMUNOGEN:	Recombinant hepatitis C virus (HCV) NS3 serine protease domain.
SPECIFICITY:	Recognizes HCV NS3 (epitope mapped to NS3 aa 160-193), recognizes NS3 alone or the NS3-4A complex.
APPLICATION:	Immunocytochemistry (1:50) Western Blot (1:500)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

Product Specific Literature References

Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines: B. Wolk, et al.; J. Virol. 74, 2293 (2000) Abstract; Full Text
Protein-protein interactions between hepatitis C virus nonstructural proteins: Dimitrova, et al.; J. Virol. 77, 5401 (2003) Abstract; Full Text
Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons: R. Gosert, et al.; J. Virol. 77, 5487 (2003) Abstract; Full Text
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes: D. Moradpour, et al.; J. Virol. 78, 7400 (2004) Abstract; Full Text
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus: E. Meylan, et al.; Nature 437, 1167 (2005) Abstract
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids: S.B. Kapadia and F.V. Chisari; PNAS 102, 2561 (2005) Abstract; Full Text
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus: E. Meylan, et al.; Nature 437, 1167 (2005) Abstract

General Information

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

Unravelling hepatitis C virus replication from genome to function: B.D. Lindenbach and C.M. Rice; Nature 436, 933 (2005) Abstract

Further Categories Containing This Product:

Monoclonal Antibodies

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