ALEXIS Biochemicals: Progranulin (mouse) ELISA Kit

AG-PM0731

Revised 23-Apr-08

Progranulin (mouse) ELISA Kit
SYNONYMS	Proepithelin (mouse) ELISA Kit PEPI (mouse) ELISA Kit PC Cell-derived Growth Factor (mouse) ELISA Kit
PRODUCT LINE	Chemokines & Cytokines
PRODUCT CATEGORY	Progranulin / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
AG-PM0731EK-KI01		96 wells	645.00 USD
AG-PM0731TP-KI01	Twin Plex	2x96 wells	945.00 USD
AG-PM0731PP-KI01	Penta Plex	5x96 wells	1'885.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Mouse
SENSITIVITY:	60pg/ml (range 0 to 16 ng/ml)
SPECIFICITY:	Does not cross-react with human and rat progranulin
APPLICATION:	For the quantitative determination of progranulin in mouse serum or cell culture supernatants.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	+4°C

General Information

Progranulin (PGRN) has been shown to be a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signalling cascades that control cell cycle progression and cell motility. PGRN has also been linked to tumorigenesis. The function of PGRN in the central nervous system (CNS) is also of interest, because mutations in the PGRN gene have been identified in cases of frontotemporal degeneration (FTD).

MANUFACTURER

Manufactured by AdipoGen, Inc.

General Literature References

Granulins, a novel class of peptide from leukocytes: A. Bateman, et al.; BBRC 173, 1161 (1990) Abstract
Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis: Z. He & A. Bateman; J. Mol. Med. 81, 600 (2003) Abstract
Progranulin is a mediator of the wound response: Z. He, et al.; Nat. Med. 9, 225 (2003) Abstract
Progranulin in frontotemporal lobar degeneration and neuroinflammation: Z. Ahmed, et al.; J. Neuroinflammation 4, 7 (2007), (Review) Abstract; Full Text
Progranulin: normal function and role in neurodegeneration: J.L. Eriksen & I.R. Mackenzie; J. Neurochem. 104, 287 (2008), (Review) Abstract

ALX-804-737	Monoclonal Antibody to Progranulin (human) (PG359-7)

AG-P0731	Progranulin (human) ELISA Kit
ALX-201-389	Progranulin (mouse) (recombinant)
ALX-201-377	Progranulin (human) (recombinant)