ALEXIS Biochemicals: Bryostatin 1

ALX-350-005

Revised 02-Oct-07

Bryostatin 1
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Other Signal Transduction Pathway Modulators

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-350-005-C010		10 µg	85.00 USD

Product Specification

FORMULA:	C₄₇H₆₈O₁₇
MW:	905.0
CAS NUMBER:	83314-01-6
MERCK INDEX:	14: 1457
PURITY:	≥97%
APPEARANCE:	Colorless oil.
SOLUBILITY:	25mg/ml soluble in 100% ethanol or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Store tightly sealed. Binds to glass and plastic surfaces in aqueous solutions.

Product Description

Binds to and activates protein kinase C (PKC). Antineoplastic.

Product Specific Literature References

Isolation and structure of Bryostatin 1: G.R. Pettit, et al.; J. Am. Chem. Soc. 104, 6846 (1982)
Bryostatin 1: differentiating agent from the depths: R.M. Stone; Leuk. Res. 21, 399 (1997) Abstract
Chemistry and clinical biology of the bryostatins: R. Mutter & M. Wills; Bioorg. Med. Chem. 8, 1841 (2000), (Review) Abstract
The clinical development of the bryostatins: A. Clamp and G.C. Jayson; Anticancer Drugs 13, 673 (2002) Abstract
The chemistry and biology of the bryostatin antitumour macrolides: K.J. Hale, et al.; Nat. Prod. Rep. 19, 413 (2002), Review Abstract
Bryostatin-1: pharmacology and therapeutic potential as a CNS drug: M.K. Sun & D.L. Alkon; CNS Drug Rev. 12, 1 (2006), Review Abstract

Further Categories Containing This Product:

Antitumor Agents (Enzyme Activators & Inducers) • PKC Activators • Natural Products - Antitumor Reagents • Natural Products - Immunomodulators

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