© 2008 Alexis Corporation
ALX-521-005 Revised 08-Jan-07
β-Nerve Growth Factor (human) (recombinant)
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SYNONYMS β-NGF (human) (recombinant)
PRODUCT LINE Chemokines & Cytokines
PRODUCT CATEGORY Nerve Growth Factors [NGF] & Receptors / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-521-005-C005   5 µg 140.00 USD Add To Cart
Product Specification
MW: ~27kDa (dimer).
CAS NUMBER: 86923-98-0
SOURCE/HOST: Produced in E. coli. Dimer of two identical subunits (119 aa) linked together by very strong hydrophobic interactions.
QUANTITY: 5µg (determined by amino acid analysis).
PURITY: ≥98% (SDS-PAGE)
FORMULATION: Lyophilized. No additives.
BIOLOGICAL ACTIVITY: ED50: 2ng/ml (determined by the dose-dependent induction of neuronal outgrowth in PC12 cells).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
USE/STABILITY: Lyophilized protein is stable for 2-3 weeks when stored at room temperature and for 6-9 months when stored at -20°C.
Reconstituted protein is stable for up to 1 week when stored at +4°C and for 4-6 weeks when stored at 80°C.
HANDLING: Avoid freeze/thaw cycles.
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General Information
Human β-NGF is responsible for survival, differentiation and maturation of sympathetic and sensory neurons.
General Literature References
The changing scene of neurotrophic factors : H. Thoenen; TINS 14, 165 (1991), (Review) Abstract
Towards a comprehensive understanding of the trophic support of motoneurons: H. Thoenen, et al.; C.R. Acad. Sci. III 316, 1158 (1193), (Review) Abstract
Neurotrophic factors enter the clinic: M. Barinaga; Science 264, 772 (1994), (Review) Abstract
Neurobiology. Tracking neurotrophin function: A.M. Davies; Nature 368, 193 (1994), (Review) Abstract
Role of neurotrophins in mouse neuronal development: R. Klein; FASEB J. 8, 738 (1994), (Review) Abstract
The neurotrophins and their receptors: structure, function, and neuropathology: L.M. Maness, et al.; Neurosci. & Biobehav. Rev. 18, 143 (1994), (Review) Abstract
Neurotrophic factors: two are better than one  : R. Nishi; Science 265, 1052 (1994), (Review) Abstract
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
 
 
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