Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids: W.A. Pryor & N.A. Porter; Free Radic. Biol. Med. 8, 541 (1990) Abstract
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes: H. Esterbauer, et al.; Free Radic. Biol. Med. 11, 81 (1991) Abstract
Quantitation of 4-hydroxynonenal protein adducts: K. Uchida & E.R. Stadtman; Meth. Enzymol. 233, 371 (1994) Abstract
Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid: Y. Ando, et al.; J. Neurol. Sci. 156, 172 (1998) Abstract
Genotoxic lipid peroxidation products: their DNA damaging properties and role in formation of endogenous DNA adducts: P.C. Burcham; Mutagenesis 13, 287 (1998) Abstract
Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system: J.N. Keller & M.P. Mattson; Rev. Neurosci. 9, 105 (1998) Abstract
4-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease: W.R. Markesbery and M.A. Lovell; Neurobiol. Aging 19, 33 (1998) Abstract
Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity: M.P. Mattson; TINS 21, 53 (1998) Abstract
Effects of 4-hydroxynonenal, a lipid peroxidation product, on dopamine transport and Na+/K+ ATPase in rat striatal synaptosomes: P. Morel, et al.; Neurochem. Int. 33, 531 (1998) Abstract
Metabolism of 4-hydroxynonenal, a cytotoxic lipid peroxidation product, in thymocytes as an effective secondary antioxidative defense mechanism: W.G. Siems, et al.; J. Biochem. 123, 534 (1998) Abstract
Oxidative alterations in Alzheimer's disease: W.R. Markesbery & J.M. Carney; Brain Pathol. 9, 133 (1999) Abstract
4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis: S. Page, et al.; J. Biol. Chem. 274, 11611 (1999) Abstract; Full Text
The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells: W.A. Pedersen, et al.; Exp. Neurol. 155, 1 (1999) Abstract
The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin: M.D. Neely, et al.; J. Neurochem. 72, 2323 (1999) Abstract
Multidrug resistance protein MRP1 protects against the toxicity of the major lipid peroxidation product 4-hydroxynonenal: J. Renes, et al.; Biochem. J. 350, 555 (2000) Abstract
The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons: S. Camandola, et al.; Brain Res. Mol. Brain Res. 85, 53 (2000) Abstract
IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2- nonenal: C. Ji, et al.; J. Biol. Chem. 276, 18223 (2001) Abstract; Full Text
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