© 2008 Alexis Corporation
ALX-550-232
Revised 13-May-08
Aconitine
SYNONYMS
(1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Neurotoxins
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-550-232-M025
25 mg
45.00 USD
Product Specification
FORMULA:
C
34
H
47
NO
11
MW:
645.7
CAS NUMBER:
302-27-2
MERCK INDEX:
14:
118
RTECS:
AR5960000
SOURCE/HOST:
Isolated from
Aconitum karacolium
.
PURITY:
≥98%
APPEARANCE:
White to off-white powder.
SOLUBILITY:
Soluble in 100% ethanol (35mg/ml); almost insoluble in water (0.3mg/ml).
SHIPPING:
AMBIENT
LONG TERM STORAGE:
+4°C
HANDLING:
Protect from light.
HAZARD:
VERY TOXIC.
Product Description
A lipid-soluble neurotoxin that acts as a sodium channel modulator. Blocks tetrodotoxin-sensitive Na
+
channels. Potent neurotoxin.
Product Specific Literature References
Non-quantal acetylcholine release at mouse neuromuscular junction: effects of elevated quantal release and aconitine:
S.P. Yu & W. Van der Kloot; Neurosci. Lett.
117
, 111 (1990)
Abstract
Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids:
M. Muroi, et al.; Neuropharmacology
29
, 567 (1990)
Abstract
Further Categories Containing This Product:
Alkaloids
•
Na+ Channels
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