ALEXIS Biochemicals: Cytochalasin E

ALX-380-062

Revised 03-Apr-08

Cytochalasin E
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics for Cytoskeletal Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-062-M001		1 mg	40.00 USD
ALX-380-062-M005		5 mg	160.00 USD

Product Specification

FORMULA:	C₂₈H₃₃NO₇
MW:	495.6
CAS NUMBER:	36011-19-5
MERCK INDEX:	14: 2790
SOURCE/HOST:	Isolated from Aspergillus clavatus.
PURITY:	≥98% (HPLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
HAZARD:	TOXIC.

Product Description

Antibiotic. Inhibits angiogenesis and tumor growth. Depolymerizes actin filaments.

Product Specific Literature References

Inhibition of actin polymerization in blood platelets by cytochalasins: J.E. Fox & D.R. Phillips; Nature 292, 650 (1981) Abstract
Cytochalasin-E-Resistant Mutants of Coprinus cinereus: Isolation and Genetic, Biochemical, and Cytological Analyses: M. Tsukamoto, et al.; Fungal Genet. Biol. 20, 52 (1996) Abstract
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth: T. Udagawa, et al.; J. Pharmacol. Exp. Ther. 294, 421 (2000) Abstract
Depolymerization of actin filament by cytochalasin E induces interleukin-8 production and up-regulates CD54 in the HeLa epithelial cell line: N. Ikewaki, et al.; Microbiol. Immunol. 47, 775 (2003) Abstract

Further Categories Containing This Product:

Interleukins Other Products • Actin / Related Products • Antibiotics for Angiogenesis Research • Microtubule Modulators • Antitumor Antibiotics • Alkaloids

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