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ALX-270-251 Revised 02-Jun-06
6(5H)-Phenanthridinone
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PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY PARP Inhibitors
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-251-M010   10 mg 15.00 USD Add To Cart
Product Specification
FORMULA: C13H9NO
MW: 195.2
CAS NUMBER: 1015-89-0
RTECS: SG0370000
PURITY: ≥95%
APPEARANCE: Light brown solid.
SOLUBILITY: Soluble in DMSO (5mg/ml).
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C

Product Description
Poly(ADP-ribose)polymerase (PARP) inhibitor.
Product Specific Literature References
Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase: M. Banasik, et al.; J. Biol. Chem. 267, 1569 (1992) Abstract; Full Text
Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor: D. Weltin, et al.; Int. J. Immunopharmacol. 17, 265 (1995) Abstract
Combination effects of poly(ADP-ribose) polymerase inhibitors and DNA-damaging agents in ovarian tumor cell lines--with special reference to cisplatin: F. Bernges & W.J. Zeller; J. Cancer Res. Clin. Oncol. 122, 665 (1996) Abstract
N-acetylcysteine protects lymphocytes from nitrogen mustard-induced apoptosis: D. Weltin, et al.; Biochem. Pharmacol. 51, 1123 (1996) Abstract
Effect of 6(5H)-phenanthridinone, a poly (ADP-ribose)polymerase inhibitor, and ionizing radiation on the growth of cultured lymphoma cells: D. Weltin, et al.; Int. J. Radiat. Biol. 72, 685 (1997) Abstract
Peroxynitrite and hydrogen peroxide induced cell death in the NSC34 neuroblastoma x spinal cord cell line: role of poly (ADP-ribose) polymerase: M.R. Cookson, et al.; J. Neurochem. 70, 501 (1998) Abstract
Effects of PARP inhibition on drug and Fas-induced apoptosis in leukaemic cells: D.S. Richardson, et al.; Adv. Exp. Med. Biol. 457, 267 (1999) Abstract
Further Categories Containing This Product:
DNA Repair Other Products
 
 
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