ALEXIS Biochemicals: Arachidonyl trifluoromethylketone

ALX-340-001

Revised 28-Jul-06

Arachidonyl trifluoromethylketone
SYNONYMS	AACOCF₃
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	PLA2 Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-340-001-M005		5 mg	70.00 USD
ALX-340-001-M010		10 mg	110.00 USD
ALX-340-001-M050		50 mg	390.00 USD

Product Specification

FORMULA:	C₂₁H₃₁F₃O
MW:	356.5
CAS NUMBER:	149301-79-1
PURITY:	≥98%
APPEARANCE:	Clear to yellow oil.
SOLUBILITY:	25mg/ml soluble in 100% ethanol or DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Dissolve in solvent purged with nitrogen or argon. Store under nitrogen or argon in tightly sealed container. Solutions are stable for up to 1 month when stored under nitrogen or argon in tightly sealed container at -80°C.
HANDLING:	PROTECT FROM AIR!
HAZARD:	TOXIC.

Product Description

Selective inhibitor of both, Ca^2+-dependent and Ca²⁺-independent phospholipase A₂(PLA₂), but not secretory PLA₂(sPLA₂). Also inhibits fatty acid amide hydrolase (FAAH) and anandamide amidase.

Product Specific Literature References

Inhibitors of arachidonoyl ethanolamide hydrolysis: B. Koutek, et al.; J. Biol. Chem. 269, 22937 (1994) Abstract; Full Text

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