ALEXIS Biochemicals: Ac-DEVD-pNA

ALX-260-033

Revised 15-Nov-06

Ac-DEVD-pNA
SYNONYMS	Caspase-3 Substrate (Chromogenic)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspase Substrates

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-033-M001		1 mg	27.00 USD
ALX-260-033-M005		5 mg	73.00 USD

Product Specification

SEQUENCE:	Ac-Asp-Glu-Val-Asp-pNA (pNA = p-Nitroaniline)
FORMULA:	C₂₆H₃₄N₆O₁₃
MW:	638.6
PEPTIDE CONTENT:	70-95%
PURITY:	≥97% (HPLC)
FORMULATION:	Lyophilized.
SOLUBILITY:	Soluble in DMSO or buffer, pH 7.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Always use fresh solutions.
HANDLING:	Keep cool and dry.

Product Description

Chromogenic substrate for caspase-3. Also a substrate for caspase-1, -4 and -7.

Product Specific Literature References

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis: D.W. Nicholson, et al.; Nature 376, 37 (1995) Abstract
Activation of the CPP32 protease in apoptosis induced by 1-beta-D- arabinofuranosylcytosine and other DNA-damaging agents: R. Datta, et al.; Blood 88, 1936 (1996) Abstract
Substrate specificities of caspase family proteases: R.V. Talanian, et al.; J. Biol. Chem. 272, 9677 (1997) Abstract; Full Text

General Information

BACKGROUND/TECHNICAL INFORMATION

λmax of pNA is 400nm.

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.