© 2008 Alexis Corporation
ALX-260-033
Revised 15-Nov-06
Ac-DEVD-pNA
SYNONYMS
Caspase-3 Substrate (Chromogenic)
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Caspase Substrates
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-260-033-M001
1 mg
27.00 USD
ALX-260-033-M005
5 mg
73.00 USD
Product Specification
SEQUENCE:
Ac-Asp-Glu-Val-Asp-pNA (pNA = p-Nitroaniline)
FORMULA:
C
26
H
34
N
6
O
13
MW:
638.6
PEPTIDE CONTENT:
70-95%
PURITY:
≥97% (HPLC)
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in DMSO or buffer, pH 7.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Always use fresh solutions.
HANDLING:
Keep cool and dry.
Product Description
Chromogenic substrate for caspase-3. Also a substrate for caspase-1, -4 and -7.
Product Specific Literature References
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis:
D.W. Nicholson, et al.; Nature
376
, 37 (1995)
Abstract
Activation of the CPP32 protease in apoptosis induced by 1-beta-D- arabinofuranosylcytosine and other DNA-damaging agents:
R. Datta, et al.; Blood
88
, 1936 (1996)
Abstract
Substrate specificities of caspase family proteases:
R.V. Talanian, et al.; J. Biol. Chem.
272
, 9677 (1997)
Abstract
;
Full Text
General Information
BACKGROUND/TECHNICAL INFORMATION
λmax of pNA is 400nm.
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