ALEXIS Biochemicals: 8-(4-Chlorophenylthio)guanosine-3',5'-cyclic-Monophosphothioate, Sp-Isomer . sodium salt

ALX-480-070

Revised 05-Dec-04

8-(4-Chlorophenylthio)guanosine-3',5'-cyclic-Monophosphothioate, Sp-Isomer . sodium salt
SYNONYMS	Sp-8-pCPT-cGMPS . Na 8-pCPT-cGMPS . Na, Sp-Isomer
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	cGMP Derivatives

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-480-070-MC05		0.5 mg	80.00 USD
ALX-480-070-M001		1 mg	140.00 USD

Product Specification

FORMULA:	C₁₆H₁₄N₅ClO₆S₂P . Na
MW:	502.9 . 23.0
CAS NUMBER:	160385-87-5
PURITY:	≥99%
APPEARANCE:	White lyophilized powder.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Potent activator of both cGMP-dependent protein kinase 1α, 1β and type II and cAMP-dependent protein kinase II. Excellent cell membrane permeability and phosphodiesterase stability.

Product Specific Literature References

(Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor: E. Butt, et al.; Eur. J. Pharmacol. 269, 265 (1994) Abstract
The type II isoform of cGMP-dependent protein kinase is dimeric and possesses regulatory and catalytic properties distinct from the type I isoforms: D.M. Gamm, et al.; J. Biol. Chem. 270, 27380 (1995) Abstract; Full Text

Further Categories Containing This Product:

PKA Activators • PKG Activators

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