ALEXIS Biochemicals: Isosorbide dinitrate

ALX-400-008

Revised 29-Apr-08

Isosorbide dinitrate
SYNONYMS	ISDN
PRODUCT LINE	Nitric Oxide Pathway
PRODUCT CATEGORY	Nitric Oxide Donors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-400-008-M100		100 mg	23.00 USD
ALX-400-008-M500		500 mg	35.00 USD

Product Specification

FORMULA:	C₆H₈N₂O₈
MW:	236.1
CAS NUMBER:	87-33-2
MERCK INDEX:	14: 5225
PURITY:	Contains ~60% lactose
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in water/acetone (1:1) (50mg/ml); sparingly soluble in water; freely soluble in organic solvents.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C
USE/STABILITY:	May be explosive upon heating.
HAZARD:	HARMFUL.

Product Description

Nitric oxide (NO) donor.

Product Specific Literature References

Isosorbide dinitrate pharmacokinetics: T. Taylor, et al.; Arzneimittelforschung 32, 1329 (1982) Abstract
Inhibition of platelet aggregation by isosorbide dinitrate: J. Ahlner, et al.; Am. J. Cardiol. 58, 665 (1986) Abstract
Inactivation of human aldehyde dehydrogenase by isosorbide dinitrate: N. Mukerjee & R. Pietruszko; J. Biol. Chem. 269, 21664 (1994) Abstract; Full Text
Effects of nitric oxide donor, isosorbide dinitrate, on energy metabolism of rat reticulocytes: S. D. Maletic, et al.; Physiol. Res. 48, 417 (1999) Abstract; Full Text
Effect of isosorbide dinitrate on nitric oxide synthase under hypoxia: H.B. Jiang, et al.; Pharmacology 62, 10 (2001) Abstract

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