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ALX-620-005 Revised 22-Feb-08
FURA 2/AM
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SYNONYMS 1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2'-amino-5'-methyl-phenoxy)ethane-N,N,N',N'-tetraacetic acid, pentaacetoxymethyl ester
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Calcium Chelators / Caged Calcium Chelators
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-620-005-M001   1 mg 135.00 USD Add To Cart
Product Specification
FORMULA: C44H47N3O24
MW: 1001.9
CAS NUMBER: 108964-32-5
PURITY: ≥98% (HPLC)
APPEARANCE: Off-white to yellow solid.
SOLUBILITY: Soluble in acetonitrile or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HANDLING: Protect from light and moisture.
IDENTITY: Determined by 1H-NMR and fluorescence.

Product Description
Cell permeable analog of FURA 2 (Prod. No. ALX-620-004). Fluorescent probe for Ca2+. After crossing the membrane, the product is quickly metabolized by cytoplasmic esterases to the membrane impermeant FURA 2.
Product Specific Literature References
Fura-2 measurement of cytosolic free Ca2+ in monolayers and suspensions of various types of animal cells: A. Malgaroli, et al.; J. Cell. Biol. 105, 2145 (1987) Abstract
A Ca2+-insensitive form of fura-2 associated with polymorphonuclear leukocytes. Assessment and accurate Ca2+ measurement: M. Scanlon, et al.; J. Biol. Chem. 262, 6308 (1987) Abstract; Full Text
Intracellular calibration of the fluorescent calcium indicator Fura-2: D.A. Williams & F.S. Fay; Cell Calcium 11, 75 (1990) Abstract
Stretch-induced increases in intracellular calcium of isolated vascular smooth muscle cells: M.J. Davis, et al.; Am. J. Physiol. 263, H1292 (1992) Abstract
Positive and negative inotropic effects of phorbol 12-myristate 13- acetate: relationship to PKC-dependence and changes in [Ca2+]i: C.A. Ward & M.P. Moffat; J. Mol. Cell. Cardiol. 24, 937 (1992) Abstract
Further Categories Containing This Product:
MDR Other Products • Calcium Indicators / Probes • Dyes / Stains / Fluorescent Probes / Fluorescent Labels
 
 
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