ALEXIS Biochemicals: Polyclonal Antibody to Clusterin (human) (AT109)

ALX-210-930

Revised 26-Feb-07

Polyclonal Antibody to Clusterin (human) (AT109)
SYNONYMS	anti-TRPM-2 (human) PAb (AT109) anti-Apolipoprotein J (human) PAb (AT109) anti-APO-J (human) PAb (AT109) anti-CLI (human) PAb (AT109) anti-CLU (human) PAb (AT109) anti-SGP-2 (human) PAb (AT109)
PRODUCT LINE	Cell Cycle
PRODUCT CATEGORY	Clusterin/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-930-C050		50 µg	180.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
SOURCE/HOST:	From rabbit
CONCENTRATION:	1mg/ml
PURITY DETAIL:	Epitope-affinity purified.
FORMULATION:	Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:	Recombinant human clusterin (aa 23-449).
SPECIFICITY:	Recognizes human clusterin.
APPLICATION:	Western Blot (1:1’000)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
POSITIVE CONTROL:	Clusterin (human) (recombinant) (Prod.No. ALX-522-089)

General Information

Clusterin (SGP-2/sulfated glycoprotein-2; CLI; Apolipoprotein J (Apo J); TRPM-2) is the first identified extracellular mammalian chaperone and appears to be implicated in such diverse processes as sperm maturation, regulation of complement activation, programmed cell death, tissue remodelling and lipid transport. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin gene expression as a prominent marker of apoptotic cell loss. A dual role has been shown for clusterin in that cells can be protected from damage and dead cells can be more easily removed after some types of cellular damage.

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate: J.G. Leger, et al.; BBRC 147, 196 (1987) Abstract
Apolipoprotein J: structure and tissue distribution: H.V. De Silva, et al.; Biochemistry 29, 5380 (1990) Abstract
Clusterin: the intriguing guises of a widely expressed glycoprotein: D.E. Jenne & J. Tschopp; Trends Biochem. Sci. 17, 154 (1992) Abstract
Clusterin: S.E. Jones and C. Jomary; Int. J. Biochem. Cell Biol. 34, 427 (2002), (Review) Abstract
Clusterin/Apolipoprotein J in human aging and cancer: I. Trougakos and E. Gonos; Int. J. Biochem. Cell Biol. 34, 1430 (2002) Abstract

Further Categories Containing This Product:

Polyclonal Antibodies

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.