© 2008 Alexis Corporation
ALX-260-155
Revised 23-Jun-08
PKCζ Pseudosubstrate (Myristoylated)
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
PKC Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-260-155-M001
1 mg
140.00 USD
Product Specification
SEQUENCE:
Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
FORMULA:
C
90
H
154
N
30
O
17
MW:
1928.4
PEPTIDE CONTENT:
≥60%
PURITY:
≥95% (HPLC)
APPEARANCE:
White to off-white powder.
FORMULATION:
Counter Ion: TFA
SOLUBILITY:
Soluble in water or DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
Product Description
Selective cell permeable inhibitor of PKCζ. Activates eNOS (NOS III) through Akt phosphorylation and can be considered as a new class of nitric oxide production activators in endothelial cells.
Product Specific Literature References
Peptides modified by myristoylation activate eNOS in endothelial cells through Akt phosphorylation:
K. Krotova, et al.; Br. J. Pharmacol.
148
, 732 (2006)
Abstract
Further Categories Containing This Product:
NOS Cofactors & Activators
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