ALEXIS Biochemicals: Pentoxifylline

ALX-270-112

Revised 16-Jun-08

Pentoxifylline
SYNONYMS	Trental 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Other Signal Transduction Pathway Modulators

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-270-112-G001		1 g	15.00 USD
ALX-270-112-G005		5 g	35.00 USD

Product Specification

FORMULA:	C₁₃H₁₈N₄O₃
MW:	278.3
CAS NUMBER:	6493-05-6
MERCK INDEX:	14: 7136
SOURCE/HOST:	Isolated from Penicillium expansum.
PURITY:	≥99%
APPEARANCE:	White solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+20°C

Product Description

Phosphodiesterase inhibitor. Blocks the synthesis of TNF-α. Improves blood flow by decreasing blood viscosity.

Product Specific Literature References

Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality: P. Noel, et al.; Life Sci. 47, 1023 (1990) Abstract
Pentoxifylline inhibits the expression of tissue factor mRNA in endotoxin-activated human monocytes: V. Ollivier, et al.; FEBS Lett. 322, 231 (1993) Abstract
Pentoxifylline: C.P. Samlaska & E.A. Winfield; J. Am. Acad. Dermatol. 30, 603 (1994), Review Abstract
Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism: K. Prasad & P. Lee; Atherosclerosis 192, 313 (2007) Abstract

Further Categories Containing This Product:

Phosphodiesterases / Related Products • TNF-alpha & TNF Receptors Other Products • Nitric Oxide Pathway Other Products

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