© 2008 Alexis Corporation
ALX-380-204
Revised 17-Jun-08
Ansatrienin B
SYNONYMS
Mycotrienin II
T 23II
PRODUCT LINE
Natural Products / Antibiotics
PRODUCT CATEGORY
Antitumor Antibiotics
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-380-204-M001
1 mg
380.00 USD
Product Specification
FORMULA:
C
36
H
50
N
2
O
8
MW:
638.8
CAS NUMBER:
82189-04-6
RTECS:
AY4553430
SOURCE/HOST:
Isolated from
Streptomyces
sp. MST-AS5998.
PURITY:
≥95% (HPLC)
APPEARANCE:
Yellow powder.
SOLUBILITY:
Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light.
HAZARD:
TOXIC.
Product Description
Antitumor antibiotic, closely related to the cytotrienins. Displays potent anticancer activities. Significantly potentiates the action of several clinical antitumor agents. Inhibits osteoclastic bone resorption.
Product Specific Literature References
Mycotrienin, a new polyene antibiotic isolated from Streptomyces:
C. Coronelli, et al.; J. Antibiot. (Tokyo)
20
, 329 (1967)
Abstract
Studies on mycotrienin antibiotics, a novel class of ansamycins. I. Taxonomy, fermentation, isolation and properties of mycotrienins I and II:
M. Sugita, et al.; J. Antibiot. (Tokyo)
35
, 1460 (1982)
Abstract
Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II:
M. Sugita, et al.; J. Antibiot. (Tokyo)
35
, 1467 (1982)
Abstract
Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluorouracil by mycotrienins and mycotrienols:
M. Kuwano, et al.; Gann.
74
, 759 (1983)
Abstract
Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption:
D. Feuerbach, et al.; J. Biol. Chem.
270
, 25949 (1995)
Abstract
;
Full Text
Further Categories Containing This Product:
Bone Metabolism Other Products
© 2008 ALEXIS Corporation,
Privacy Policy
,
Disclaimer
,
Feedback
another
CS2
website
