ALEXIS Biochemicals: Diacylglycerol Kinase Inhibitor I (R59 022)

ALX-430-027

Revised 05-Dec-04

Diacylglycerol Kinase Inhibitor I (R59 022)
SYNONYMS	6-[2-(4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl)ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidine-5-one
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Diacylglycerol Kinases / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-027-M005		5 mg	115.00 USD

Product Specification

FORMULA:	C₂₇H₂₆FN₃OS
MW:	459.6
CAS NUMBER:	93076-89-2
PURITY:	≥99%
APPEARANCE:	Yellow powder.
SOLUBILITY:	Soluble in DMSO, THF or DMF. Insoluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C

Product Description

Potentiates the activity of protein kinase C (PKC) by inhibiting the diacylglycerol metabolism. Inhibits diacylglycerol kinase without affecting phosphodiesterase or phosphatidyl inositol kinase.

Product Specific Literature References

R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet: D. de Chaffoy de Courcelles, et al.; J. Biol. Chem. 260, 15762 (1985) Abstract; Full Text

Further Categories Containing This Product:

PKC Activators

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