ALEXIS Biochemicals: Cytochalasin C

ALX-380-069

Revised 26-Jun-08

Cytochalasin C
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics for Cytoskeletal Research

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-069-M001		1 mg	60.00 USD
ALX-380-069-M005		5 mg	240.00 USD

Product Specification

FORMULA:	C₃₀H₃₇NO₆
MW:	507.6
CAS NUMBER:	22144-76-9
MERCK INDEX:	14: 2790
RTECS:	HA5300500
SOURCE/HOST:	Isolated from Metarhizium anisopliae.
PURITY:	≥98% (TLC)
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in DMSO, 100% ethanol or dichloromethane.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.
HAZARD:	MAY BE TERATOGENIC. VERY TOXIC.

Product Description

Antibiotic. Disrupts the actin microfilament cytoskeleton and inhibits the cytoplasmic dividing of a cell. Has been found to be ten times less toxic in mice than cytochalasin D (Prod. No. ALX-380-031) but with essentially the same biological effectiveness against cells in culture.

Product Specific Literature References

Actin assembly activity of cytochalasins and cytochalasin analogs assayed using fluorescence photobleaching recovery: E.A. Walling, et al.; Arch. Biochem. Biophys. 264, 321 (1988) Abstract
Alteration in cell morphology triggers transforming growth factor-beta 1, collagenase, and tissue inhibitor of metalloproteinases-I expression in normal and hypertrophic scar fibroblasts: M. Varedi, et al.; J. Invest. Dermatol. 104, 118 (1995) Abstract

Further Categories Containing This Product:

Microtubule Modulators • Alkaloids

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