© 2008 Alexis Corporation
ALX-550-213 Revised 06-Jun-08
(±)-BAY K 8644
Add to Clipboard
SYNONYMS 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)-phenyl]pyridine-3-carboxylic acid methyl ester
PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Ca2+ Channels (L-type)
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-550-213-M005   5 mg 80.00 USD Add To Cart
ALX-550-213-M025   25 mg 320.00 USD Add To Cart
Product Specification
FORMULA: C16H15F3N2O4
MW: 356.3
CAS NUMBER: 93468-89-4
PURITY: ≥98% (HPLC)
APPEARANCE: Yellow powder.
SOLUBILITY: Soluble in DMSO, 100% ethanol or methanol; slightly soluble in water.
SHIPPING: AMBIENT
LONG TERM STORAGE: +4°C

Product Description
Potent, direct acting, voltage-sensitive Ca2+ channel (L-type) agonist.
Product Specific Literature References
The optical isomers of the 1,4-dihydropyridine BAY K 8644 show opposite effects on Ca channels: G. Franckowiak, et al.; Eur. J. Pharmacol. 114, 223 (1985) Abstract
BAY-K-8644, a calcium channel agonist, induces a rise in cytoplasmic free calcium and iodide discharge in thyroid cells: N. Takasu, et al.; BBRC 143, 1107 (1987) Abstract
Goldstein, et al.; Drug Dev. Res. 11, 59 (1987)
Calcium channel ligands: D.J. Triggle & R.A. Janis; Ann. Rev. Pharmacol. Toxicol. 27, 347 (1987) Abstract
1,4-Dihydropyridine activators and antagonists: structural and functional distinctions: D.J. Triggle & D. Rompe; TIPS 10, 507 (1989) Abstract
 
 
© 2008 ALEXIS Corporation, Privacy Policy, Disclaimer, Feedbackanother CS2 website