ALEXIS Biochemicals: ACP

ALX-430-118

Revised 14-Apr-08

ACP
SYNONYMS	1-Acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Oxidative Stress Markers & Reagents / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-118-M010		10 mg	65.00 USD
ALX-430-118-M050		50 mg	195.00 USD
ALX-430-118-M250		250 mg	490.00 USD

Product Specification

FORMULA:	C₁₁H₂₀N₂O₃
MW:	228.3
PURITY:	≤0.05% paramagnetic impurities (by EPR)
APPEARANCE:	White to off-white crystalline powder.
SOLUBILITY:	Soluble in water, methanol, 100% ethanol or DMSO.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C

Product Description

Cell permeable probe for the detection of intracellular oxidative stress. ACP can easily be deprotected with esterases to cyclic hydroxylamines, which are oxidized by ROS leading to ESR-detectable nitroxide radicals.

Product Specific Literature References

Sensitive ESR determination of intracellular oxidative stress by using acyl-protected hydroxylamines as new spin reagents: O. Itoh, et al.; Chem. Lett. 304 (2000)
In vivo EPR imaging by using an acyl-protected hydroxylamine to analyze intracerebral oxidative stress in rats after epileptic seizures: H. Yokoyama, et al.; Magn. Reson. Imaging 18, 875 (2000) Abstract
Measurement of oxidative stress by EPR radical-probe technique: L. Valgimigli, et al.; Free Radical Biol. Med. 31, 708 (2001), (Review) Abstract
Pharmacokinetic study of acyl-protected hydroxylamine probe, 1-acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine, for in vivo measurements of reactive oxygen species: K. Saito, et al.; Free Radic. Biol. Med. 36, 517 (2004) Abstract

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.