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ALX-630-050 Revised 10-Oct-08
β-Bungarotoxin
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SYNONYMS β-BuTx
PRODUCT LINE Natural Products / Antibiotics
PRODUCT CATEGORY Neurotoxins
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-630-050-M001   1 mg 60.00 USD Add To Cart
Product Specification
MW: 6979.0
CAS NUMBER: 12778-32-4
MERCK INDEX: 14: 1488
SOURCE/HOST: Isolated from Bungarus multicinctus.
PURITY: ≥98%
APPEARANCE: Lyophilized.
SOLUBILITY: Soluble in water or aqueous buffers.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
HAZARD: HARMFUL.
Product Description
Presynaptic, neurotoxic phospholipase A2 activity.
Product Specific Literature References
Use of a snake venom toxin to characterize the cholinergic receptor protein: J.P. Changeux, et al.; PNAS 67, 1241 (1970) Abstract
Amino acid sequence of alpha-bungarotoxin from the venom of Bungarus multicinctus: D. Mebs, et al; BBRC 44, 711 (1971) Abstract
Alpha-bungarotoxin binding and central nervous system nicotinic acetylcholine receptors: R.E. Oswald; Neuroscience 6, 1 (1981) Abstract
Amino acid sequence of beta 2-bungarotoxin from Bungarus multicinctus venom. The amino acid substitutions in the B chains: K. Kondo, et al.; J. Biochem. 91, 1519 (1982) Abstract
Amino acid sequences of three beta-bungarotoxins (beta 3-, beta 4-, and beta 5- bungarotoxins) from Bungarus multicinctus venom. Amino acid substitutions in the A chains: K. Kondo; J. Biochem. 91, 1531 (1982) Abstract
Biochemical and electrophysiological demonstrations of the actions of beta-bungarotoxin on synapses in brain: J.V. Halliwell; J. Neurochem. 39, 543 (1982) Abstract
Solubilization and characterization of the beta-bungarotoxin-binding protein of chick brain membranes: H. Rehm & H. Betz; J. Biol. Chem. 259, 6865 (1984) Abstract; Full Text
Beta-bungarotoxin inhibits a non-inactivating potassium current in guinea pig dorsal root ganglion neurones: M. Petersen, et al.; Neurosci. Lett. 68, 141 (1986) Abstract
Cross-linking of beta-bungarotoxin to chick brain membranes. Identification of subunits of a putative voltage-gated K+ channel: R.R. Schmidt & H. Betz; Biochemistry 28, 8346 (1989) Abstract
Nucleotide sequence encoding beta-bungarotoxin A2-chain from the venom glands of Bungarus multicinctus: J.M. Danse, et al.; Nucl. Acids Res. 18, 4609 (1990) Abstract
Potassium channel toxins: P.N. Strong; Pharmacol. Ther. 46, 137 (1990), (Review) Abstract
Mechanism of action of beta-bungarotoxin, a presynaptically acting phospholipase A2 neurotoxin: its effect on protein phosphorylation in rat brain synaptosomes: E. Ueno & P. Rosenberg; Toxicon 34, 1219 (1996) Abstract
What does beta-bungarotoxin do at the neuromuscular junction?: E.G. Rowan; Toxicon 39, 107 (2001), (Review) Abstract
Induction by beta-bungarotoxin of apoptosis in cultured hippocampal neurons is mediated by Ca(2+)-dependent formation of reactive oxygen species: O. Shakhman, et al.; J. Neurochem. 87, 598 (2003) Abstract
Phospholipase A(2) activity of beta-bungarotoxin is essential for induction of cytotoxicity on cerebellar granule neurons: Y.J. Chen; J. Neurobiol. 64, 213 (2005) Abstract
Mechanism of beta-bungarotoxin in facilitating spontaneous transmitter release at neuromuscular synapse: J.C. Liou, et al.; Neuropharmacology 51, 671 (2006) Abstract
Further Categories Containing This Product:
K+ Channel Blockers & InhibitorsPLA2
 
 

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