ALEXIS Biochemicals: PTMIO, free radical

ALX-430-145

Revised 25-Apr-07

PTMIO, free radical
SYNONYMS	4-Phenyl-2,2,5,5-tetramethyl-3-imidazoline-1-oxyl nitroxide
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Free Radicals/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-145-M050		50 mg	45.00 USD
ALX-430-145-M250		250 mg	180.00 USD
ALX-430-145-G001		1 g	510.00 USD

Product Specification

FORMULA:	C₁₃H₁₇N₂O
MW:	217.3
CAS NUMBER:	39753-69-0
PURITY:	≥99% (¹H-NMR, EPR)
APPEARANCE:	Orange solid.
PURITY DETAIL:	No paramagnectic impurities detected by EPR.
SOLUBILITY:	Soluble in 100% ethanol, DMSO, acetone, chloroform or hexane. Insoluble in water.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C

Product Description

Free radical similar to 4-Amino-TEMPO (Prod. No. ALX-400-019) and 3-Carboxy-2,2,5,5-tetramethyl-1-
pyrrolidine-1-oxyl (Prod. No. ALX-400-018), but more lipophilic than the former compounds. May be useful for membrane dynamic studies.

Product Specific Literature References

Probing the intracellular redox status of tumors with magnetic resonance imaging and redox-sensitive contrast agents: F. Hyodo, et al.; Cancer Res. 66, 9921 (2006) Abstract

General Literature References

Neuroprotective effects of the stable nitroxide compound Tempol on 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in the Nerve Growth Factor-differentiated model of pheochromocytoma PC12 cells: T. Lipman, et al.; Eur. J. Pharmacol. 549, 50 (2006) Abstract
Determining the topology of integral membrane peptides using EPR spectroscopy: J.J. Inbaraj, et al.; J. Am. Chem. Soc. 128, 9549 (2006) Abstract

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