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ALX-260-131 Revised 10-Apr-08
Z-Phe-Arg-AMC . hydrochloride
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SYNONYMS Z-FR-AMC . HCl
PRODUCT LINE Cancer
PRODUCT CATEGORY Cathepsin Substrates
Ordering Information
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ALX-260-131-M005   5 mg 30.00 USD Add To Cart
Product Specification
SEQUENCE: Z-Phe-Arg-AMC (AMC=7-Amino-4-methyl coumarin)
FORMULA: C33H36N6O6 . HCl
MW: 612.7 . 36.5
CAS NUMBER: 65147-22-0
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
Product Description
Fluorogenic substrate for cathepsin B and L, papain, plasma kallikrein and soy bean trypsin-like enzyme.
Product Specific Literature References
New fluorogenic substrates for alpha-thrombin, factor Xa, kallikreins, and urokinase: T. Morita, et al.; J. Biochem. (Tokyo) 82, 1495 (1977) Abstract
Fluorimetric assays for cathepsin B and cathepsin H with methylcoumarylamide substrates: A.J. Barrett; Biochem. J. 187, 909 (1980) Abstract
Cathepsin B, Cathepsin H, and cathepsin L: A.J. Barrett & H. Kirschke; Methods Enzymol. 80, 535 (1981) Abstract
Rapid interaction of cathepsin L by Z-Phe-PheCHN12 and Z-Phe-AlaCHN2: H. Kirschke & E. Shaw; BBRC 101, 454 (1981) Abstract
Action of rat liver cathepsin L on collagen and other substrates: H. Kirschke, et al.; Biochem. J. 201, 367 (1982) Abstract
Kinetic investigation of soybean trypsin-like enzyme catalysis: M. Nishikata; J. Biochem. (Tokyo) 97, 1001 (1985) Abstract
Photometric or fluorometric assay of cathepsin B, L and H and papain using substrates with an aminotrifluoromethylcoumarin leaving group: J.R. Tchoupe, et al.; Biochim. Biophys. Acta 1076, 149 (1991) Abstract
 
 
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