ALEXIS Biochemicals: Baccatin III, 10-Deacetyl-

ALX-351-006

Revised 07-Jan-08

Baccatin III, 10-Deacetyl-
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Natural Products - Antitumor Reagents

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-351-006-M005		5 mg	190.00 USD
ALX-351-006-M025		25 mg	590.00 USD

Product Specification

FORMULA:	C₂₉H₃₆O₁₀
MW:	544.6
CAS NUMBER:	32981-86-5
SOURCE/HOST:	Isolated from Taxus baccata.
PURITY:	≥95%
SOLUBILITY:	Soluble in DMSO.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Protect from light and moisture. Avoid strong oxidizing agents, acids and bases.

Product Description

Intermediate for the preparation of taxol analogs.

Product Specific Literature References

Relationships between the structures of taxol and baccatine III derivatives and their in vitro action on the disassembly of mammalian brain and Physarum amoebal microtubules: H. Lataste, et al.; PNAS 81, 4090 (1984) Abstract
Chemical Studies of 10-Deacetyl Baccatin III. Hemisynthesis of Taxol Derivatives: F. Gueritte-Voegelein, et al.; Tetrahedron Letters 42, 4451 (1986)
A highly efficient, practical approach to natural taxol: J.-N. Denis, et al.; JACS 110, 5917 (1988)
Preclinical evaluation of docetaxel (Taxotere): F. Lavelle, et al.; Semin. Oncol. 22, 3 (1995) Abstract

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