© 2008 Alexis Corporation
ALX-260-077
Revised 10-Feb-05
Ac-DMQD-CHO
SYNONYMS
Caspase-3 Inhibitor (Aldehyde)
PRODUCT LINE
Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY
Caspase Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-260-077-M001
1 mg
62.00 USD
ALX-260-077-M005
5 mg
243.00 USD
Product Specification
SEQUENCE:
Ac-Asp-Met-Gln-Asp-CHO
FORMULA:
C
20
H
31
N
5
O
10
S
MW:
533.6
PEPTIDE CONTENT:
70-90%.
PURITY:
≥96% (HPLC)
APPEARANCE:
White powder.
FORMULATION:
Lyophilized.
SOLUBILITY:
Soluble in distilled water.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
USE/STABILITY:
Stock solutions should be divided into aliquots and stored at -20°C.
HANDLING:
Keep cool and dry.
Product Description
Reversible inhibitor of caspase-3. Together with the caspase-6 inhibitor Ac-VEID-CHO (Prod. No.
ALX-260-062
) this inhibitor has been used to dissect the pathway of caspase activation in Fas-stimulated Jurkat cells.
Product Specific Literature References
Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis:
H. Hirata, et al.; J. Exp. Med.
187
, 587 (1998)
Abstract
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