ALEXIS Biochemicals: DIPPMPO

ALX-430-119

Revised 31-Jul-07

DIPPMPO
SYNONYMS	5-(Diisopropoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Spin Traps, Spin Probes & Spin Labels

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-119-M050		50 mg	160.00 USD
ALX-430-119-M500		500 mg	1'120.00 USD

Product Specification

FORMULA:	C₁₁H₂₂NO₄P
MW:	263.3
PURITY:	≥98% (¹H-NMR)
APPEARANCE:	Colorless crystals.
SOLUBILITY:	Soluble in water, 100% ethanol or methylene chloride.
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	-20°C
LONG TERM STORAGE:	-80°C
HANDLING:	Protect from light. Hygroscopic.

Product Description

Beside DEPMPO (Prod. No. ALX-430-093), most efficient spin trap for the in vitro and in vivo detection of O-, N-, S-, and C-centered free radicals. Has a longer life-time than DMPO (Prod. No. ALX-430-129). More lipophilic (Kp=2.1) than DEPMPO.

Product Specific Literature References

5-(Diisopropoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide, DIPPMPO, a crystalline analog of the nitrone DEPMPO: synthesis and spin trapping properties: F. Chalier & P. Tordo; J. C. S. Perkin Trans. II 2002, 2110 Abstract
The line asymmetry of electron spin resonance spectra as a tool to determine the cis:trans ratio for spin-trapping adducts of chiral pyrrolines N-oxides: the mechanism of formation of hydroxyl radical adducts of EMPO, DEPMPO, and DIPPMPO : M. Culcasi, et al.; Free Radic. Biol. Med. 40, 1524 (2006) Abstract