ALEXIS Biochemicals: Cyclosporin C

ALX-380-282

Revised 19-Mar-08

Cyclosporin C
SYNONYMS	Thr²-cyclosporin A 7-L-Threonine-cyclosporin A
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antibiotics - Immunomodulators

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-282-M001		1 mg	50.00 USD
ALX-380-282-M005		5 mg	200.00 USD

Product Specification

FORMULA:	C₆₂H₁₁₁N₁₁O₁₃
MW:	1218.6
CAS NUMBER:	59787-61-0
MERCK INDEX:	14: 2752
SOURCE/HOST:	Isolated from Fusarium solani.
PURITY:	≥95% (HPLC)
APPEARANCE:	Colorless to off-white crystalline solid.
SOLUBILITY:	Soluble in 100% ethanol, acetone or ethyl acetate; insoluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	MAY BE CARCINOGENIC. TOXIC. MAY BE TERATOGENIC.

Product Description

Potent immunosuppressor.

Product Specific Literature References

Cyclosporin A and C-New metabolites from Trichodermapolysporum (Link ex Pers.) Rifai: M. Dreyfuss, et al.; Europ. J. Appl. Microbiol. 3, 125 (1976)
[The structure of cyclosporin c (author’s transl)]: R. Traber, et al.; Helv. Chim. Acta 60, 1247 (1977) Abstract
Dosage, timing, and route of administration of cyclosporin A and nonimmunosuppressive derivatives of dihydrocyclosporin A and cyclosporin C against Schistosoma mansoni in vivo and in vitro: L.H. Chappell, et al.; Antimicrob. Agents Chemother. 31, 1567 (1987) Abstract
Cyclosporin C is the main antifungal compound produced by Acremonium luzulae: M. Moussaif, et al.; Appl. Environ. Microbiol. 63, 1739 (1997) Abstract; Full Text
Cyclosporin C(2) and C(0) concentration monitoring in stable, long-term heart transplant recipients receiving metabolic inhibitors: J.E. Ray, et al.; J. Heart Lung Transplant. 22, 715 (2003) Abstract

Further Categories Containing This Product:

Non-apoptotic Cell Death / Necrosis

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