© 2008 Alexis Corporation
ALX-430-141
Revised 14-Nov-06
BMPO (high purity)
SYNONYMS
5-
tert
-Butoxycarbonyl-5-methyl-1-pyrroline-N-oxide (high purity)
PRODUCT LINE
Oxidative Stress
PRODUCT CATEGORY
Spin Traps, Spin Probes & Spin Labels
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-430-141-M010
10 mg
70.00 USD
ALX-430-141-M050
50 mg
280.00 USD
Product Specification
FORMULA:
C
10
H
17
NO
3
MW:
199.3
PURITY:
≥99% (
1
H-NMR, EPR)
APPEARANCE:
White to off-white crystalline solid.
SOLUBILITY:
Soluble in water.
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from moisture.
Product Description
Nitrone spin trap for the specific
in vivo
or
in vitro
detection of short-lived superoxide, hydroxyl and thiyl radicals. Forms distinguishable adducts which can be measured by EPR spectroscopy. Unlike with DMPO, the superoxide adduct does not decay into a hydroxyl adduct and it has a much longer half-life (t
1/2
=23min). Low paramagnetic impurities. No further purification required.
Product Specific Literature References
Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals:
H. Zhao, et al.; Free Radic. Biol. Med.
31
, 599 (2001)
Abstract
Spin traps: in vitro toxicity and stability of radical adducts:
N. Khan, et al.; Free Radic. Biol. Med.
34
, 1473 (2003)
Abstract
Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence:
H. Zhao, et al.; PNAS
102
, 5727 (2005)
Abstract
Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species:
H. Shi, et al.; Arch. Biochem. Biophys.
437
, 59 (2005)
Abstract
© 2008 ALEXIS Corporation,
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