© 2008 Alexis Corporation
ALX-270-313
Revised 03-Mar-05
BPIQ-I
SYNONYMS
8-[(3-Bromophenyl)amino]-3-methyl-3
H
-imidazo[4,5-γ]-quinazoline
PRODUCT LINE
Signal Transduction
PRODUCT CATEGORY
EGFR Kinase Inhibitors
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
Add To Cart
ALX-270-313-M001
1 mg
140.00 USD
Product Specification
FORMULA:
C
16
H
12
BrN
5
MW:
354.2
PURITY:
≥95%
APPEARANCE:
Off white to yellow solid.
SOLUBILITY:
Soluble in DMSO.
SHIPPING:
AMBIENT
LONG TERM STORAGE:
-20°C
HANDLING:
Protect from light. Keep under inert gas.
Product Description
Potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC
50
=25 pM).
Product Specific Literature References
Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor:
G.W. Rewcastle, et al.; J. Med. Chem.
39
, 918 (1996)
Abstract
Further Categories Containing This Product:
Tyrosine Kinase Inhibitors
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