ALEXIS Biochemicals: Guanosine 5'-O-(3-thiotriphosphate) . tetralithium salt

ALX-480-056

Revised 26-Mar-08

Guanosine 5'-O-(3-thiotriphosphate) . tetralithium salt
SYNONYMS	GTP-γ-S . 4Li
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	Guanosine Derivatives Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-480-056-M001		1 mg	45.00 USD
ALX-480-056-M005		5 mg	180.00 USD

Product Specification

FORMULA:	C₁₀H₁₂N₅O₁₃P₃S . 4Li
MW:	535.2 . 27.8
CAS NUMBER:	94825-44-2
PURITY:	≥88%
APPEARANCE:	White to off-white solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Analog of guanosine 5'-O-triphosphate (GTP) with resistance to enzymatic hydrolysis. Stimulates inositol trisphosphate formation in membranes.

Product Specific Literature References

G proteins: transducers of receptor-generated signals: A.G. Gilman; Ann. Rev. Biochem. 56, 615 (1987) Abstract
Guanosine 5'-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C: S. Orellana, et al.; J. Biol. Chem. 262, 1638 (1987) Abstract; Full Text
A functional role for GTP-binding proteins in synaptic vesicle cycling: S.D. Hess, et al.; Science 259, 1169 (1993) Abstract

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