ALEXIS Biochemicals: RSSR

ALX-430-102

Revised 04-Jun-08

RSSR
SYNONYMS	bis-(2,2,5,5-Tetramethyl-3-imidazoline-1-oxyl-4-yl)disulfide, biradical
PRODUCT LINE	Oxidative Stress
PRODUCT CATEGORY	Spin Traps, Spin Probes & Spin Labels

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-102-M010		10 mg	70.00 USD
ALX-430-102-M025		25 mg	140.00 USD
ALX-430-102-M050		50 mg	240.00 USD

Product Specification

FORMULA:	C₁₄H₂₄N₄O₂S₂
MW:	344.5
PURITY:	≥97% (HPLC)
APPEARANCE:	Off-white to yellow powder.
SOLUBILITY:	Soluble in DMSO, water, 100% ethanol or methanol; DMSO is recommended for stock solution.
SHIPPING:	SHIPPED ON DRY ICE
LONG TERM STORAGE:	-20°C
HANDLING:	Protect from light.

Product Description

Cell permeable supersensitive spin label (detection limit varies from 10nM to 100nM) for quick detection of reduced thiols using ESR. Allows following the reactions of sulfhydryl groups with RSSR to form thiol spin label adducts, for the monitoring of intracellular redox states of glutathione and other thiols.

Product Specific Literature References

Quantitative determination of SH groups in low- and high-molecular-weight compounds by an electron spin resonance method: V.V. Khramtsov, et al.; Anal. Biochem. 182, 58 (1989) Abstract
Quantitative determination of thiol groups in low and high molecular weight compounds by electron paramagnetic resonance: L.M. Weiner; Meth. Enzymol. 251, 87 (1995) Abstract
Quantitative determination and reversible modification of thiols using imidazolidine biradical disulfide label: V.V. Khramtsov, et al.; J. Biochem. Biophys. Methods 35, 115 (1997) Abstract
Use of imidazoline nitroxides in studies of chemical reactions. ESR measurements of the concentration and reactivity of protons, thiols and nitric oxide.: V.V. Khramtsov & L. B. Volodarsky; Spin labeling. The next Millennium. 145, 109 (1998)
Unique in vivo applications of spin traps: L.J. Berliner, et al.; Free Radic. Biol. Med. 30, 489 (2001) Abstract
In vitro and in vivo measurement of pH and thiols by EPR-based techniques: V.V. Khramtsov, et al.; Antioxid. Redox. Signal. 6, 667 (2004) Abstract

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