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ALX-270-343 Revised 30-May-07
3-O-Methyl-N-acetyl-D-glucosamine
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SYNONYMS 3-OMe-GlcNAc
PRODUCT LINE Obesity & Adipokines
PRODUCT CATEGORY Carbohydrates
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-270-343-M005   5 mg 190.00 USD Add To Cart
Product Specification
FORMULA: C9H17NO6
MW: 235.2
CAS NUMBER: 94825-74-8
PURITY: ≥98% (1H-NMR)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in DMSO (10mg/ml) or water (10mg/ml).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
HANDLING: Protect from light.
HAZARD: HARMFUL.

Product Description
Inhibitor of N-acetylglucosamine kinase (Ki=17µM) and N-acetylmannosamine kinase (Ki=80µM). It has been found that 3-OMe-GlcNAc potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine.
Product Specific Literature References
Inhibition of N-acetylglucosamine kinase and N-acetylmannosamine kinase by 3-O-methyl-N-acetyl-D-glucosamine in vitro: R. Zeitler, et al.; Eur. J. Biochem. 204, 1165 (1992) Abstract
Utility of 3-O-methyl-N-acetyl-D-glucosamine, an N-acetylglucosamine kinase inhibitor, for accurate assay of glucokinase in pancreatic islets and liver: I. Miwa, et al.; Enzyme Protein 48, 135 (1994) Abstract
Further Categories Containing This Product:
Obesity & Diabetes Other Products • N-Acetylneuraminic Acid / Derivatives
 
 
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