ALEXIS Biochemicals: cAMP-dependent Protein Kinase Substrate

ALX-151-019

Revised 15-Dec-04

cAMP-dependent Protein Kinase Substrate
SYNONYMS	PKA Substrate
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	PKA Substrates

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-151-019-MC05		0.5 mg	95.00 USD
ALX-151-019-M001		1 mg	165.00 USD

Product Specification

SEQUENCE:	H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH
FORMULA:	C₉₂H₁₅₀N₂₈O₂₉
MW:	2112.4
PURITY:	≥95%
APPEARANCE:	White powder.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C

Product Description

Derived from the RII subunit of cAMP-dependent protein kinase (PKA). Substrate for PKA. Has been used in a non-radioactive assay of calcineurin (protein phosphatase 2B) for screening purposes.

Product Specific Literature References

Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity: D.K. Blumenthal, et al.; J. Biol. Chem. 261, 8140 (1986) Abstract; Full Text
Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP-dependent protein kinase as substrate: A. Enz, et al.; Anal. Biochem. 216, 147 (1994) Abstract

Further Categories Containing This Product:

PP2B [Calcineurin] / Related Products • Peptides