ALEXIS Biochemicals: Monoclonal Antibody to HERG1 (human) (A12)

ALX-804-652

Revised 22-Feb-07

Monoclonal Antibody to HERG1 (human) (A12)
SYNONYMS	anti-Erg1 (human) MAb (A12) anti-Ether-a-go-go Related Protein 1 (human) MAb (A12) anti-KCNH2 (human) MAb (A12) anti-Voltage-gated Potassium Channel Subfamily H Member 2 (human) MAb (A12) anti-Voltage-gated Potassium Channel Kv11.1 (human) MAb (A12)
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	K+ Channel Antibodies

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-652-R300		300 µl	390.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human
CLONE:	A12
ISOTYPE:	Mouse IgG2b
FORMULATION:	Liquid. Ascites.
IMMUNOGEN:	Synthetic peptide corresponding to aa 575-588 (E⁵⁷⁵QPHMDSRIGWLHN⁵⁸⁸) of the extracellular loop S5-P of HERG1 (human ether-a-go-go related protein 1).
SPECIFICITY:	Recognizes the extracellular loop S5-P of HERG1.
APPLICATION:	Flow Cytometry (1:2-1:50) Immunocytochemistry (1:50-1:200) Immunohistochemistry (paraffin sections) (1:50-1:200) Immunoprecipitation (3-5µl)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

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General Information

The ether-a-go-go related gene family of K⁺ channels (HERG/Erg) comprises three members, HERG1/Erg1, HERG2/Erg2, HERG3/Erg3. HERG channel activity is relevant to tumor cell biology. It controls cell proliferation, especially in leukaemias. HERG channels are thus considered novel diagnostic and prognostic factors in human cancers, as well as targets for anti-neoplastic therapies.

Further Categories Containing This Product:

Monoclonal Antibodies • Cancer Other Products

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