© 2008 Alexis Corporation
ALX-210-069
Revised 16-Jul-08
Polyclonal Antibody to HIF-1α
SYNONYMS
anti-Hypoxia-inducible Factor 1α PAb
anti-ARNT-interacting Protein PAb
PRODUCT LINE
Oxidative Stress
PRODUCT CATEGORY
Hypoxia-inducible Factor [HIF] / Related Products
Ordering Information
Product Numbers:
Format:
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Unit Price:
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ALX-210-069-C050
50 µg
220.00 USD
Product Specification
SPECIES CROSSREACTIVITY:
Human
Mouse
SOURCE/HOST:
From rabbit.
CONCENTRATION:
2.8mg/ml
PURITY DETAIL:
Protein G-affinity purified.
FORMULATION:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
IMMUNOGEN:
Recombinant HIF-1α (hypoxia-inducible factor-1a) (aa 609-826).
SPECIFICITY:
Recognizes human and mouse HIF-1α.
APPLICATION:
Immunohistochemistry (1:200)
Immunoprecipitation (1-5µg)
Western Blot (1µg/ml)
SHIPPING:
SHIPPED ON BLUE ICE
LONG TERM STORAGE:
-20°C
HANDLING:
Avoid freeze/thaw cycles.
Product Specific Literature References
Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis:
N. Tang, et al.; Cancer Cell
6
, 485 (2004)
Abstract
Epidermal sensing of oxygen is essential for systemic hypoxic response:
A.T. Boutin, et al.; Cell
133
, 206 (2008)
Abstract
Critical Role of HIF-1alpha in Keratinocyte Defense against Bacterial Infection:
C. Peyssonnaux, et al.; J. Invest. Dermatol.
128
, 1964 (2008)
Abstract
General Literature References
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin
:
C. C. Hudson, et al.; Mol. Cell Biol.
22
, 7004 (2002)
Abstract
;
Full Text
Further Categories Containing This Product:
Aryl Hydrocarbon Receptor / Related Products
•
Polyclonal Antibodies
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