ALEXIS Biochemicals: Kendomycin

ALX-380-066

Revised 07-Apr-08

Kendomycin
SYNONYMS	(-)-TAN 2162
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antitumor Antibiotics

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-066-C100		100 µg	95.00 USD
ALX-380-066-C500		500 µg	370.00 USD

Product Specification

FORMULA:	C₂₉H₄₂O₆
MW:	486.6
CAS NUMBER:	59785-91-0
SOURCE/HOST:	Isolated from Streptomyces violaceoruber.
PURITY:	≥98%
APPEARANCE:	Yellow powder.
SOLUBILITY:	Soluble in DMSO or methanol.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HAZARD:	TOXIC.

Product Description

Potent endothelin receptor antagonist. Anti-osteoporotic compound. Shows remarkable antibacterial and cytotoxic activity. Mediates its cytotoxic effects, at least in part, through proteasome inhibition.

Product Specific Literature References

2000 Structure and biosynthesis of kendomycin, a carboxylic ansa-compound from Streptomyces: A.Zeeck & H.B. Bode; J. Chem. Soc. Perkin Trans. 323 (2000)
Evidence for the mode of action of the highly cytotoxic Streptomyces polyketide kendomycin: Y.A. Elnakady, et al.; Chembiochem. 8, 1261 (2007) Abstract

Further Categories Containing This Product:

Antibiotics - Other Signal Transduction Pathway Modulators • Endothelins [ETs] & Endothelin Receptors/Related Products • Antibiotics - Proteasome/Ubiquitin Modulators • Bone Metabolism Other Products

another CS2 website

Online Product Ordering

Clipboard [0]

Your items will be kept only for the duration of your visit.