© 2008 Alexis Corporation
ALX-430-131 Revised 16-May-08
CAT1H . hydrochloride
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SYNONYMS 1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-yl-trimethylammonium chloride . HCl
PRODUCT LINE Oxidative Stress
PRODUCT CATEGORY Spin Traps, Spin Probes & Spin Labels
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-430-131-M010   10 mg 65.00 USD Add To Cart
ALX-430-131-M050   50 mg 195.00 USD Add To Cart
ALX-430-131-M250   250 mg 450.00 USD Add To Cart
Product Specification
FORMULA: C12H27ClN2O . HCl
MW: 250.8 . 36.5
APPEARANCE: White to off-white solid.
PURITY DETAIL: Paramagnetic impurities ≤0.01% (EPR).
SOLUBILITY: Soluble in water, methanol or 100% ethanol.
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
HANDLING: Protect from moisture.

Product Description
Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections. Lifetime of more than 4 hours in blood plasma, in cells and tissue. Allows quantitative measurements of extracellular O2•– and quantification of intracellular O2•– in cells and tissue samples and in vivo O2•– detection.
Product Specific Literature References
Role of extracellular superoxide dismutase in hypertension: M.C. Gongora, et al.; Hypertension 48, 473 (2006) Abstract; Full Text
Measurement of reactive oxygen species in cardiovascular studies: S. Dikalov, et al.; Hypertension 49, 717 (2007) Abstract
Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction: T.J. Guzik, et al.; J. Exp. Med. 204, 2449 (2007) Abstract; Full Text
Mitochondrial redox cycling of mitoquinone leads to superoxide production and cellular apoptosis: A.K. Doughan & S.I. Dikalov; Antioxid. Redox Signal. 9, 1825 (2007) Abstract