ALEXIS Biochemicals: N-Acetyl-N-acetoxy-4-chlorobenzenesulphonamide

ALX-430-021

Revised 17-Jan-05

N-Acetyl-N-acetoxy-4-chlorobenzenesulphonamide
PRODUCT LINE	Nitric Oxide Pathway
PRODUCT CATEGORY	Nitric Oxide Pathway Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-430-021-M005		5 mg	40.00 USD

Product Specification

FORMULA:	C₁₀H₁₀ClNO₅S
MW:	291.7
PURITY:	≥98%
APPEARANCE:	White crystals.
SOLUBILITY:	Soluble in DMSO or DMF; slightly soluble in methanol; not soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C

Product Description

Nitroxyl (HNO) releasing compound in neutral solution. Release of nitric oxide was not detected. Potent vasorelaxant. Powerful inhibitor of aldehyde dehydrogenase.

Product Specific Literature References

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase: M.J.C. Lee, et al.; J. Med. Chem. 35, 3648 (1992) Abstract
N,O-diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties: J.M. Fukuto, et al.; BBRC 187, 1367 (1992) Abstract

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