© 2008 Alexis Corporation
ALX-201-233
Revised 22-Jun-07
Rad9/Rad1/Hus1 (human) (recombinant)
SYNONYMS
9-1-1 Complex (human) (recombinant)
PRODUCT LINE
Cell Cycle
PRODUCT CATEGORY
DNA Damage Checkpoint Other Products
Ordering Information
Product Numbers:
Format:
Size:
Unit Price:
Quantity:
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ALX-201-233-C005
5 µg
240.00 USD
Product Specification
MW:
106kDa (heterotrimer of 43, 31 and 32kDa)
SOURCE/HOST:
Produced in baculovirus.
CONCENTRATION:
1mg/ml
PURITY:
≥90% (by SDS-PAGE).
FORMULATION:
Liquid. In 25mM Tris, pH 8.0, containing 20% glycerol, 100mM sodium chloride and 1mM β-mercaptoethanol.
SHIPPING:
SHIPPED ON DRY ICE
LONG TERM STORAGE:
-80°C
HANDLING:
After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
Product Specific Literature References
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair:
M. Toueille, et al.; Nucl. Acids Res.
32
, 3316 (2004)
Abstract
;
Full Text
The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery:
E. Smirnova, et al.; Biochem. J.
389
, 13 (2005)
Abstract
General Literature References
Regulation of the DNA replication fork: a way to fight genomic instability:
M. Toueille and U. Hubscher; Chromosoma
113
, 113 (2004)
Abstract
Further Categories Containing This Product:
Recombinant Proteins / Fusion Proteins
•
DNA Replication Other Products
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