ALEXIS Biochemicals: Polyclonal Antibody to ZBP1 (mouse) (AT132)

ALX-210-957

Revised 23-Apr-08

Polyclonal Antibody to ZBP1 (mouse) (AT132)
SYNONYMS	anti-Z-DNA-binding Protein 1 (mouse) PAb (AT132) anti-Tumor Stroma And Activated Macrophage Protein DLM-1 (mouse) PAb (AT132) anti-DAI (mouse) PAb (AT132) anti-DNA-dependent Activator of IFN-regulatory Factors (mouse) PAb (AT132)
PRODUCT LINE	Immunology
PRODUCT CATEGORY	Innate Immunity Other Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-210-957-C100		100 µg	350.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Mouse
SOURCE/HOST:	From rabbit.
CONCENTRATION:	1mg/ml
PURITY:	Protein A-affinity purified.
FORMULATION:	Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:	Recombinant mouse ZBP1 (aa 1-411) fused to a N-terminal tag.
SPECIFICITY:	Recognizes mouse ZBP1.
APPLICATION:	Immunoprecipitation (1:200) Western blot (1:1’000)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
HANDLING:	Avoid freeze/thaw cycles.

General Information

ZBP1 is a cytoplasmic recognition receptor that senses and is activated by DNA from several sources. Upon activation, ZBP1 triggers a type I IFN response through the activation of IRF3 and, probably, IRF7.
MANUFACTURER	Manufactured by Apotech Corporation.

General Literature References

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response: A. Takaoka, et al.; Nature 448, 501 (2007) Abstract