ALEXIS Biochemicals: Ac-LEHD-AMC

ALX-260-080

Revised 11-Dec-07

Ac-LEHD-AMC
SYNONYMS	Caspase-9 Substrate (Fluorogenic)
PRODUCT LINE	Cell Death / Apoptosis / Autophagy
PRODUCT CATEGORY	Caspase Substrates

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-260-080-M001		1 mg	42.00 USD
ALX-260-080-M005		5 mg	163.00 USD

Product Specification

SEQUENCE:	Ac-Leu-Glu-His-Asp-AMC (AMC=7-Amino-4-methylcoumarin)
FORMULA:	C₃₃H₄₁N₇O₁₁
MW:	711.7
PEPTIDE CONTENT:	75-95%
PURITY:	≥98%
APPEARANCE:	White to off-white powder.
SOLUBILITY:	Soluble in DMSO or phosphate buffer, pH 7.5.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	-20°C
HANDLING:	Keep cool and dry.

Product Description

Fluorogenic substrate for caspase-9.

Product Specific Literature References

Bid truncation, bid/bax targeting to the mitochondria, and caspase activation associated with neutrophil apoptosis are inhibited by granulocyte colony-stimulating factor: N.A. Maianski, et al.; J. Immunol. 172, 7024 (2004) Abstract
Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells: J. Hofmanova; Eur. J. Nutrition 44, 40 (2005)

General Information

BACKGROUND/TECHNICAL INFORMATION

AMC has an excitation maximum of 380nm and an emission maximum of 460nm.

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