ALEXIS Biochemicals: Guanosine-3',5'-cyclic Monophosphothioate, Sp-Isomer . sodium salt

ALX-480-073

Revised 06-Dec-04

Guanosine-3',5'-cyclic Monophosphothioate, Sp-Isomer . sodium salt
SYNONYMS	Sp-cGMPS . Na cGMPS . Na, Sp-Isomer
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	cGMP Derivatives

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-480-073-MC05		0.5 mg	95.00 USD
ALX-480-073-M001		1 mg	150.00 USD

Product Specification

FORMULA:	C₁₀H₁₁N₅O₆SP . Na
MW:	360.3 . 23.0
CAS NUMBER:	86562-10-9 (free acid)
PURITY:	≥98%
APPEARANCE:	White solid.
SOLUBILITY:	Soluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C

Product Description

Metabolically resistant activator of cGMP-dependent protein kinases (PKGs). Low membrane permeability.

Product Specific Literature References

Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3',5'- monophosphorothioates: E. Butt, et al.; FEBS Lett. 263, 47 (1990) Abstract
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase: S.L. Archer, et al.; PNAS 91, 7583 (1994) Abstract
Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp)-8-bromo-PET-cyclic GMPS: E. Butt, et al.; Br. J. Pharmacol. 116, 3110 (1995) Abstract

Further Categories Containing This Product:

PKG Activators

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