ALEXIS Biochemicals: Actinomycin X2

ALX-380-080

Revised 03-Apr-08

Actinomycin X2
PRODUCT LINE	Natural Products / Antibiotics
PRODUCT CATEGORY	Antitumor Antibiotics

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-380-080-M001		1 mg	70.00 USD

Product Specification

FORMULA:	C₆₂H₈₄N₁₂O₁₇
MW:	1269.4
SOURCE/HOST:	Isolated from Streptomyces sp.
PURITY:	≥95% (solvent free)
APPEARANCE:	Orange crystals.
SOLUBILITY:	Soluble in methanol, acetone or chloroform.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HANDLING:	Keep cool and dry.
HAZARD:	TOXIC.
IDENTITY:	Determined by ¹H-NMR: Identical to standard reference.

Product Description

Antitumor antibiotic. Has higher cytotoxicity toward cultured human leukemia (HL-60) cells than actinomycin D (Prod. No. ALX-380-009). Induces cell death via apoptosis.

Product Specific Literature References

Nomenclature of the Actinomycins: S.A. Waksman, et al.; PNAS 44, 602 (1958) Abstract
Correlation of actinomycin X2 to the lipid profile in static and shaken cultures of Streptomyces nasri strain YG62: M.Y. el-Naggar, et al.; Microbios. 100, 117 (1999) Abstract
Characterization of Streptomyces MITKK-103, a newly isolated actinomycin X2-producer: K. Kurosawa, et al.; Appl. Microbiol. Biotechnol. 72, 145 (2006) Abstract

Further Categories Containing This Product:

Antibiotics - Apoptosis Inducers & Inhibitors • Transcription Inhibitors / Related Products

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