ALEXIS Biochemicals: Monoclonal Antibody to CTRP7 (Anna-1)

ALX-804-835

Revised 04-Jan-07

Monoclonal Antibody to CTRP7 (Anna-1)
SYNONYMS	anti-C1q Tumor Necrosis Factor-α-related Protein 7 MAb (Anna-1) anti-C1qTNF7 MAb (Anna-1)
PRODUCT LINE	Obesity & Adipokines
PRODUCT CATEGORY	C1q Tumor Necrosis Factor-alpha-related Proteins [CTRPs]

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-804-835-C100		100 µg	320.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse
CLONE:	Anna-1
ISOTYPE:	Mouse IgG1
SOURCE/HOST:	Purified from concentrated hybridoma tissue culture supernatant.
CONCENTRATION:	1mg/ml
PURITY:	≥95% (SDS-PAGE)
FORMULATION:	Liquid. In PBS containing 0.02% sodium azide.
IMMUNOGEN:	Recombinant mouse CTRP7 (C1q tumor necrosis factor-α-related protein 7) (aa 18-290).
SPECIFICITY:	Recognizes human and mouse CTRP7.
APPLICATION:	ELISA Immunohistochemistry (paraffin sections) Immunoprecipitation (1:200) Western Blot (1:1’000)
SHIPPING:	SHIPPED ON BLUE ICE
SHORT TERM STORAGE:	+4°C
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 1 year after receipt when stored at -20°C.
HANDLING:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.

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General Information

Adiponectin is involved in controlling the whole-body metabolism, particularly by increasing insulin sensitivity in muscle and liver, and by increasing fatty acid oxidation in muscle. CTRP7 belongs to a new highly conserved family of adiponectin paralogs designated as C1q tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. A member of this family, CTRP2 (mouse) has been reported to rapidly induce phosphorylation of AMP-activated protein kinase, acetyl-CoA carboxylase, and mitogen-activated protein kinase in C2C12 myotubes, which resulted in increased glycogen accumulation and fatty acid oxidation.

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

A family of Acrp30/adiponectin structural and functional paralogs: G.W. Wong, et al.; PNAS 101, 10302 (2004) Abstract

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Monoclonal Antibodies

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