ALEXIS Biochemicals: Adiponectin (mouse) (recombinant)

ALX-522-059

Revised 02-Mar-07

Adiponectin (mouse) (recombinant)
SYNONYMS	ACRP30 (mouse) (recombinant) Adipocyte Complement Related Protein of 30kDa (mouse) (recombinant) AdipoQ (mouse) (recombinant) apM1 (mouse) (recombinant) GBP28 (mouse) (recombinant)
PRODUCT LINE	Obesity & Adipokines
PRODUCT CATEGORY	Adiponectin [ACRP30]/Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-522-059-C050		50 µg	335.00 USD

Product Specification

SPECIES CROSSREACTIVITY:	Mouse
MW:	~35kDa (SDS-PAGE).
SOURCE/HOST:	Produced in HEK 293 cells. Mouse adiponectin (aa 18-247) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG^®-tag.
CONCENTRATION:	0.5mg/ml after reconstitution.
PURITY:	≥90% (SDS-PAGE)
FORMULATION:	Lyophilized. Contains PBS.
ENDOTOXIN CONTENT:	<0.1EU/µg purified protein (LAL test; Bio Whittaker).
RECONSTITUTION:	Reconstitute with 100µl sterile water.
BIOLOGICAL ACTIVITY:	Inhibits serum glucose production in mice. Protects mouse hepatocytes from TNF-α-induced cell death in vitro.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C
USE/STABILITY:	Stable for at least 6 months after receipt when stored at -20°C.
HANDLING:	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

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Product Description

Mimics serum adiponectin by forming high molecular weight (HMW) and hexameric species.

Product Specific Literature References

Regulation of T-cell mediated hepatic inflammation by adiponectin and leptin: J.A. Sennello, et al.; Endocrinology 146, 2157 (2005) Abstract

General Information

BACKGROUND/TECHNICAL INFORMATION

Swiss-Prot link Q60994: Adiponectin (mouse)

FLAG is a registered trademark of Sigma-Aldrich Co.

MANUFACTURER

Manufactured by Apotech Corporation.

General Literature References

Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30): T.S. Tsao, et al.; J. Biol. Chem. 277, 29359 (2002) Abstract; Full Text
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity: U.B. Pajvani, et al.; J. Biol. Chem. 279, 12152 (2004) Abstract; Full Text

Further Categories Containing This Product:

Recombinant Proteins/Fusion Proteins

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