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ALX-420-041 Revised 21-Feb-08 New product
WS-12
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SYNONYMS (2S,5R)-2-Isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboximide
PRODUCT LINE Neurobiology
PRODUCT CATEGORY Neuroactive Agents Other Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-420-041-M001   1 mg 25.00 USD Add To Cart
ALX-420-041-M005   5 mg 75.00 USD Add To Cart
ALX-420-041-M025   25 mg 280.00 USD Add To Cart
Product Specification
FORMULA: C18H27NO2
MW: 289.4
PURITY: ≥98% (HPLC)
APPEARANCE: White to off-white powder.
SOLUBILITY: Soluble in 100% ethanol, methanol, ethyl acetate, methylene chloride, dimethyl formamide or acetonitrile; insoluble in water or DMSO.
SHIPPING: AMBIENT
LONG TERM STORAGE: -20°C
IDENTITY: Determined by 1H-NMR and MS.

Product Description
Cooling agent. High-affinity TRPM8 (cold menthol receptor 1; CMR1) agonist. Has an EC50 value ~2’000 times lower than that of (-)-menthol (Prod. No. ALX-420-042).
Product Specific Literature References
Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators: B. Beck, et al.; Cell Calcium 41, 285 (2007) Abstract
Characterisation of TRPM8 as a pharmacophore receptor: M. Bodding, et al.; Cell Calcium 42, 618 (2007) Abstract
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