ALEXIS Biochemicals: Diethylmaleate

ALX-280-017

Revised 31-Oct-06

Diethylmaleate
SYNONYMS	2-Butenedioic acid
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	NF-kB Pathway Inhibitors

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
ALX-280-017-G005		5 g	15.00 USD

Product Specification

FORMULA:	C₈H₁₂O₄
MW:	172.2
CAS NUMBER:	141-05-9
MERCK INDEX:	14: 3123
RTECS:	ON1225000
PURITY:	≥97%
APPEARANCE:	Clear liquid.
SOLUBILITY:	Soluble in 100% ethanol or ether; insoluble in water.
SHIPPING:	AMBIENT
LONG TERM STORAGE:	+4°C
HAZARD:	MAY BE MUTAGENIC. IRRITANT. MAY BE CARCINOGENIC.

Product Description

Reduces NF-κB activation through the formation of conjugates with NF-κB.

Product Specific Literature References

Acrolein causes inhibitor kappaB-independent decreases in nuclear factor kappaB activation in human lung adenocarcinoma (A549) cells: N.D. Horton, et al.; J. Biol. Chem. 274, 9200 (1999) Abstract; Full Text

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